Palmitoyl Tetrapeptide-7, commonly referred to as PAL-7 is a lipopeptide composed of the tetrapeptide sequence glycine-L-glutamine-L-proline-L-arginine (GQPR) conjugated with palmitic acid.
PAL-7 belongs to the palmitoylated peptide class of cosmetic ingredients and is supplied as a raw peptide powder for professional cosmetic formulation.
Purity: Greater than (>) 99% Purity
Sizes Available: 100 mg, 250 mg, 500 mg, 1 G - 100 G and up
Bulk Sizes Also Available
Product Features
• Cosmetic-grade palmitoylated peptide raw material
• Synthetic Palmitoyl Tetrapeptide-7 (Pal-GQPR)
• Four-amino-acid peptide sequence: Gly-Gln-Pro-Arg
• Palmitoylated derivative of the GQPR tetrapeptide
• Powder format for formulation flexibility
• Suitable for professional cosmetic formulation and manufacturing
• Suitable for laboratory and product-development applications
• Commonly incorporated into advanced peptide-based skincare formulations
• Supplied as a raw ingredient for further processing
Product Description
Palmitoyl Tetrapeptide-7 is a synthetic lipopeptide formed by conjugating palmitic acid to the tetrapeptide sequence glycine-glutamine-proline-arginine (Gly-Gln-Pro-Arg or GQPR). The addition of the palmitoyl group creates a lipophilic derivative of the GQPR peptide and distinguishes Palmitoyl Tetrapeptide-7 from its non-palmitoylated peptide sequence.
The molecule combines a four-amino-acid peptide sequence with a C16 fatty-acid chain derived from palmitic acid. This structural modification increases the lipophilic character of the molecule, making PAL-7 particularly relevant to the development of topical cosmetic formulations and advanced peptide-based ingredient systems.
Palmitoyl Tetrapeptide-7 is widely recognized as a cosmetic peptide ingredient and is frequently incorporated into sophisticated skincare formulation concepts, particularly formulations developed for the appearance of mature and environmentally stressed skin. PubChem identifies Palmitoyl Tetrapeptide-7 as a cosmetic ingredient and references its Cosmetic Ingredient Review assessment.
PAL-7 is also commonly formulated alongside other cosmetic peptides, including Palmitoyl Tripeptide-1 (Pal-GHK). Commercial cosmetic peptide complexes containing both Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 are available for professional formulation applications.
Cosmetic Formulation Applications
Palmitoyl Tetrapeptide-7 is supplied for incorporation into professionally developed cosmetic and personal care formulations. Its concentrated powder format provides flexibility for laboratory-scale development, prototype formulation, manufacturing, and peptide ingredient-system evaluation.
Potential formulation categories include:
• Cosmetic serums
• Anti-aging cosmetic formulations
• Facial creams and lotions
• Eye-area cosmetic formulations
• Gel and emulsion-based formulations
• Moisturizing and conditioning products
• Multi-peptide skincare formulations
• Peptide-containing skincare systems
• Professional cosmetic product development
• Laboratory formulation and stability testing
Compatibility, processing conditions, concentration, pH, solubilization method, preservation systems, and stability should be determined by the formulator for each finished formulation.
Handling & Storage
Keep the material tightly sealed and protected from excessive heat, light, and moisture. Storage conditions should follow the recommendations provided with the product's batch documentation or Certificate of Analysis.
As with other peptide raw materials, unnecessary exposure to moisture and repeated temperature fluctuations should be minimized. Appropriate laboratory handling procedures should be followed when weighing, transferring, or incorporating the powder into formulations.
Intended Use
For cosmetic formulation and manufacturing purposes only. Not intended for injection, ingestion, or use as a pharmaceutical product. This product is not intended to diagnose, treat, cure, or prevent disease.
The purchaser and finished-product manufacturer are responsible for determining appropriate formulation conditions, ingredient compatibility, concentration, stability, safety, labeling, and compliance with all applicable regulations.
Technical Specifications
Chemical Name: N-Palmitoyl-glycyl-L-glutaminyl-L-prolyl-L-arginine
Molecular Formula: C₃₄H₆₂N₈O₇
Physical Form: Powder
Typical Appearance: White to off-white powder
Solubility: Solubility dependent on pH, solvent system, and formulation conditions
Application Category: Cosmetic and Personal Care Formulation
Grade: Cosmetic Grade